Great Lakes Clinical Trials Initiates Early-Stage Alzheimer's Study Targeting Tau Proteins

A clinical research study is ongoing to study the effects of an investigational Anti-Tau antibody called ABBV-8E12 in patients with early stage Alzheimer's disease.

The progression of abnormal Tau proteins in the brain is strongly associated with clinical progression of disease and resulting decline in brain function. 

The video below describes the science behind this novel approach to targeting the source of Alzheimer's disease.

If you are interested in learning more about this research study, call our Patient Care Representatives at (773) 275-3500 or click HERE to visit our study webpage.

Migraine Study Enrolling Now

Great Lakes Clinical Trials is looking for volunteers for a clinical research study for people that have frequent migraine headaches on a monthly basis. The investigational study medication is in a new class of drugs called calcitonin gene-related peptide receptor antagonists or CGRPs.

You may be able to participate if you:
• Are between 18 to 75 years of age
• Suffer from 2-8 migraines a month
• Have a history of migraines lasting between 7-72 hours
• Are able to make 4 clinic visits over the course of 2-3 months

Note that participants will be allowed to remain on standard migraine prophylactic medications (eg, betablockers, tricyclic antidepressants, topiramate, valproic acid, or botox) as long as the treatment has been stable for at least 30 days prior to screening and will remain unchanged during the course of the trial.

Qualified participants will receive:
· Study related care and office visits at no cost. Insurance is not required
· Investigational study medication at no cost
· Qualified participants will receive up to $250 for their participation in this study.

If you are interested in joining this trial, click here and choose the "SIGN UP" button to provide your contact information.  One of our staff will be in touch with you within 24 hrs to conduct a short phone screen to determine your eligibility.   Otherwise, you can call our center directly at (773) 275-3500 to speak with one of our staff today.

Nutritional Shake Research Study for Patients with Type 2 Diabetes

GREAT LAKES CLINICAL TRIALS is currently seeking participants for a new clinical trial
assessing the effects of nutritional shakes on glucose levels in patients with Type 2 Diabetes.

Supplemental nutrition drinks (or shakes) provide a healthy balance of protein, carbohydrate, and fat, vitamins and minerals. Diabetes-specific nutritional shakes are specially designed to deliver nutrition and minimize blood glucose spikes after consumption. When used as part of a diabetes management plan, they can help blood glucose control.

THE GOAL of our study is to assess to evaluate the impact of a complete and balanced
diabetes-specific nutritional shake consumed twice daily, on glucose control. Glucose levels will
be measured through a continuous glucose monitor which you will wear throughout the course
of the study.

TO QUALIFY, for this research study, you must be:

• generally healthy
• 30 years old, or older
• current taking oral diabetes medications at least 2 months. You will stay on your current diabetes treatment during the trial.

In addition, you must have an HbA1C value between 7-10%. We will perform a finger stick
measurement at your first visit to confirm, or in case you are not aware of your HbA1c value.

THE STUDY INVOLVES 3 VISITS TO OUR CLINIC. There will be three visits to our clinic on Day 1, Day 6 and Day 14.

• The first visit may last up to 90 minutes. After receiving your study information and
obtaining your consent to proceed, we will perform a fingerstick HbA1C measurement
to determine if your values are in the acceptable range to participate in the study. If
your HbA1c levels fall between 7 and 10% we will continue the visit to evaluate your
health to participate in the trial. If not, you will not be able to continue in the study.
During this first visit we will place a continuous glucose monitor on the back of your
upper arm.
• The second and third visits may last up to an hour.
• There will be a phone call 2-7 days after the study for safety follow-up.

COMPENSATION.  Qualified participants will receive up to $200 for their participation in this
study. Study related care and office visits are provided at no cost. Insurance is not required

TO LEARN MORE about this research program, visit our website at
www.greatlakesclinicaltrials.com or call our Patient Care Representatives at (773) 275-3500.

Probiotics in a Snack Bar?

Great Lakes Clinical Trials is looking for male and female volunteers between the ages of 18 and 65 for a investigational research study involving the consumption of a daily snack bar. Participants will be randomly assigned to consume either a standard snack bar or a snack bar containing a probiotic for a 4 week period.

The purpose of the study is to measure levels of the probiotic that pass through your gut and appear in your stool. The study will require you to collect your stool on 4 separate occasions throughout the 6-week study period. You will be provided with a stool collection kit and transport systems.

You may be able to participate if you:

  • are of slender build, having a body mass index between 18.5-29.9 kg/m2. Our study staff can help determine this over the phone.
  • have not taken any probiotics in last 4 weeks or antibiotics in the past 6 weeks.
  • have not made any substantial dietary changes or significant weight changes in the past 4 weeks.
  • do not have a history or presence of any GI condition, such as inflammatory bowel disease, IBS, chronic constipation, bowel movement irregularity or eating disorder.

Note other entry criteria will apply and can be discussed with our study staff

You will be asked to visit our clinic on 6 occasions over approximately 6 weeks. One visit is simply to drop off a stool sample. The other 5 visits last between 30-90 minutes.

There is no cost for participation in this study. All medications, tests and doctor visits are free of charge and we do not bill insurance. For your participation, you will receive $25 for visits 1, 2 & 3 and $75 for visits 4, 5, and 6, for a total of up to $300 for completing the trial.

Want to learn more? Visit us at www.greatlakesclinicaltrials.com or call (773) 275-3500.

Great Lakes Clinical Trials Featured in Daily Herald Article

Great Lakes Clinical Trials is proud to have been featured in today's "Healthy You" section of the Chicagoland's leading suburban newspaper, The Daily Herald.

FAMILIES PLACE THEIR HOPES IN ALZHEIMER'S RESEARCH

Today's Daily Herald Article Featuring Great Lakes Clinical Trials

Today's Daily Herald Article Featuring Great Lakes Clinical Trials

January 27, 2017
Daily Herald - Healthy You Section
Page 4


Misplacing keys, forgetting someone’s name or blanking on a phone number. We don’t pay much attention to these memory lapses when we are young; however, as we age we may start to worry about what they mean.

It’s important to know the difference between normal forgetfulness and the symptoms of a more serious problem, such as Alzheimer’s disease.

Alzheimer’s disease is more than memory loss. It is a brain disease that may remain “silent” for many years before noticeable symptoms start to show. Researchers believe Alzheimer’s can start to affect the structure of the brain as early as age 40. Eventually the disease progresses to a point where obvious symptoms can be seen, such as memory loss, reduced decision making skills or confusion with time and place.

Great Lakes Clinical Trials is a research organization committed to finding a way to stop, slow down or even prevent Alzheimer’s disease.

“We are at a time when research is advancing rapidly,” said Steve Satek, president of Great Lakes Clinical Trials and member of the Medical and Scientific Advisory Board for the Alzheimer’s Association’s Greater Illinois Chapter. “A noninvasive imaging technique called Positron Emission Tomography (PET scans) has allowed us to see inside the brains of humans and identify buildup of amyloid plaques and neurofibrillary tau tangles, that are believed to be the source of Alzheimer’s disease. A few years back the only way to visualize plaques and tangles was through an autopsy.”

PET scans are among several new procedures available to identify individuals who may be living in the “silent phase” of the disease.These individuals have little-to-no symptoms of memory loss, but a PET scan may show the signs of Alzheimer’s disease inside their brain. Researchers believe that if the medical community can break up or reduce the amount of plaques and tangles in these individuals, then these people may have a greater chance of delaying memory loss.

Promising, investigational medications that target this source of Alzheimer’s disease are now being studied in the Chicago area, at clinics like Great Lakes Clinical Trials. For these new treatments to be approved by the FDA and become available by prescription, they must first be studied in clinical trials.

“Some people I meet say they don’t want to know if they are in the silent phase. They tell me there is nothing they can do about it, so they don’t want to know,” Satek said. “I see why people may first respond that way, but when they learn of the advancements in research and the opportunities in clinical trials, they tend to change their view. They see hope.”

Across the country, volunteers for clinical trials are needed now, or this challenge will be passed to future generations. “Most of the patients we see are participating as part of their legacy.
They are doing it for their children and grandchildren,” Satek said. “Participation in clinical trials is free, including the PET scans. Insurance is not required. Patients remain under the care or their regular doctor and our board-certified physicians simply provide supplemental care. Great Lakes
may even provide free transportation for clinic visits.”

There truly is hope for a prevention or cure for Alzheimer’s disease. Whether someone has no noticeable signs of memory loss, or if they are starting to experience memory problems that are affecting daily activities, joining a research study is an option.

To learn how you can help be the solution to ending Alzheimer’s disease, call Great Lakes Clinical Trials at (773) 275-3500 or visit www.greatlakesclinicaltrials.com.

Great Lakes Clinical Trials Initiates New Alzheimer's Disease Prevention Trial

Great Lakes Clinical Trials is proud to announce the initiation of an exciting new clinical trial to assess the effectiveness of an investigational medication for preventing progression to Alzheimer's disease.  

Steve Satek, President of Great Lakes Clinical Trials, speaks frequently across the Chicagoland area on the topic of Alzheimer’s disease research:

"Many local seniors approach me, asking what they can do to help win the fight against Alzheimer's disease.  Financial donations to groups like the Alzheimer's Association do a great deal to help support research activities, however the only way we will every find the first medication to prevent, cure or simply slow down the progression of Alzheimer's disease is through the clinical trial process. That means we have an immediate need for senior volunteers to participate in studies to assess whether these medications are safe and effective.
I find that many people don’t fully understand the meaning of prevention studies and don’t know how to get involved. Our biggest challenge is getting the word out about these studies.  Once they hear about these programs, and visit our state-of-the-art clinic, they become very motived – particularly seniors who have a history of Alzheimer’s in their family.  If seniors don’t participate now to help find a cure, then the burden of studying these new medications simply gets passed down generations, to their children and grandchildren – and meanwhile, more and more seniors will continue to be diagnosed with Alzheimer’s. The time to act is now."

The new Alzheimer’s disease prevention study at Great Lakes Clinical Trials is called the “EARLY Trial”.  You can learn more about this program by visiting the study website at www.earlytrial.com.

The Alzheimer’s Association has reported that Alzheimer’s disease is the 6th leading cause of death in the United States and that 1-in-3 seniors will die of Alzheimer’s disease or another form of dementia.  It is also important to note, that beside the emotional burden placed on family caregivers, it is estimated that family caregivers spend over $5,000 a year caring for their loved one.  For some families, this means missing a vacation, but for many others, it may mean going hungry.   So, there is a clear, urgent need to find a prevention or even a way to slow down the disease.

Satek added:

"The way I explain Alzheimer’s prevention trials, is that we first need to engage motivated, generally healthy seniors, typically over the age of 60, who are currently not experiencing any memory problems. In addition to ensuring safety through medical exams and assessments of memory and cognition, we provide an investigational medication or a placebo (an inactive substance like a sugar pill) to these patients and follow them closely for several years.  Over time, we can determine if the investigational mediation is working better than the placebo to prevent or slow down the progression to Alzheimer’s disease. 
It’s important to note that participation in our research studies is always at no financial cost to our patients, including all doctor visits, exams and tests. We do not bill insurance or Medicare. Great Lakes Clinical Trials is located on the ground floor with direct street-level access - very conveneint for seniors. We even have free parking and we provide free transportation for some of our trials."

If you are interested in learning more about the different types of research studies offered by Great Lakes Clinical Trials, you can view our current study list by clicking here or you can always call our patient care representatives by calling (773) 275-3500.

Great Lakes Clinical Trials Initiates Migraine Study With Novel Investigational Drug

Great Lakes Clinical Trials has initiated a new study to assess the effectiveness and safety of a new class of medication in migraine sufferers.  This study is being conducted under the leadership of Great Lakes Clinical Trials' board-certified neurologist, John Lavaccare, MD and will begin enrolling patients on January 3rd.

You can learn more about this program on our study-specific web page by clicking here.

Great Lakes Clinical Trials Kicks Off Participation in GeneMatch Program

Great Lakes Clinical Trials is proud to be an active participant in GeneMatch.  The goal of this program is to move Alzheimer’s research forward by helping scientists recruit participants who may qualify for prevention studies.

ABOUT THE STUDY

GeneMatch is a research program of the Alzheimer’s Prevention Registry to identify a large group of people interested in participating in Alzheimer’s research studies based on their genetic information. 

The information you provide will remain secure and confidential. It will be used to help potentially connect you to research studies. Whether you pursue participation in a study is entirely up to you. You are under no obligation to join any study opportunity that may be offered and can remove yourself from GeneMatch at any time.

PURPOSE

The Alzheimer’s Prevention Registry created the GeneMatch program to help match people who are 55- 75 years old to research studies based on their genetic information.

WHAT IS INVOLVED?

GeneMatch will provide you with a cheek swab kit to determine which copies of a gene (known as the APOE type allele) you have. You will not be told your APOE genotype as part of the GeneMatch Program.

GeneMatch may contact you about study opportunities or other based on your APOE genotype. Your interest and response to these study opportunities may be recorded and tracked by the GeneMatch team. You may be invited to complete online education modules and surveys.

Participants will be asked questions regarding the learning material and answers will be recorded and tracked by the GeneMatch team.

Click HERE to learn more and sign up!

 

Great Lakes Clinical Trials Offers Complimentary Memory Screenings

In support of November being National Alzheimer’s Disease Awareness Month, Great Lakes Clinical Trials will be offering complimentary memory screenings at their new clinic located on the campus of the Lutheran Home in Arlington Heights, IL. 

The event will take place on Friday, November 18th between the hours of 9am and 5pm. 

Appointments must be made in advance by calling (847) 368-7404.

Worried About Your Cholesterol? Don't Like Taking Medications?

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Great Lakes Clinical Trials is looking for participants for a research study assessing the effectiveness of a DIETARY SUPPLEMENT on individuals with slightly elevated cholesterol levels.  The dietary supplement being studied contains plant sterols and stanols, also known as “phytosterols”.  These are substances that are naturally found in plant foods, including fruits, vegetables and vegetable oils, nuts and seeds.  

The study lasts approximately 17 weeks and participants will come to our clinic for 7 visits.  To qualify, you must:

  • Be between 21-79 years old and in generally health
  • Have elevated LDL cholesterol as verified by finger stick blood test at your first visit
  • Not currently be taking medications or over-the-counter supplements for high cholesterol
  • Be able to follow a diet to maintain body weight throughout the study
  • Have not been diagnosed with diabetes or have uncontrolled high blood pressure
  • Not be currently taking antidepressants

Our research is conducted by board-certified physicians under Good Clinical Practice (GCP) guidelines.  All services at Great Lakes Clinical Trials is free of charge, meaning you will not be charged for study-related care, medications, or exams.

For this study, you will receive up to $350 for your participation.

Click here TO SIGN UP or call 773-275-3500